In early 2016, the long-time owners of Stien Designs & Graphics in Kendallville, Indiana, told their customers they were going to retire. One of their customers, Monica Corbin, had always been interested in crafting and sewing, so she thought it might be a nice lifestyle change. However, she realized it was not feasible for her to operate the business on her own. After talking with her friend Andrea Beachy and realizing that Andrea had past experience with screen printing, the two decided to give it a shot. Betty Lou Designs & Graphics is the result of their efforts (and is named after a combination of their middle names, Betty and Lou).